A new research study, written and conducted by Barry Pittendrigh and Kent Walters, and published in the Journal of Toxicological Sciences addresses the effects of the very powerful illicit drug, methamphetamine.
The study suggests that similar to when humans who are exposed to methamphetamine, fruit flies who are exposed to the drug drastically increase their physical activity and decrease the amount of food they consume.
The study found that starvation was the primary characteristic involving those that died of methamphetamine-related deaths as the study tracked behavioral and metabolic changes in fruit flies administered methamphetamine.
According to the study, many harsh consequences result from chronic use of methamphetamine, including significant side effects such as, altered energy metabolism in the brain as well as death of brain cells. Additionally, the bones, heart and muscles are severely weakened, and the body is burdened with toxic metabolic by products.
Previous studies revealed that drosophilia melanogasters were most ideal creatures for laboratory research, not to mention the most common.
However, the recently published study indicates that fruit flies are just as ideal for studying the effects that methamphetamine produce with respect to the brain and body.
Research conducted thus far has led researchers to the conclusion that the toxicological effects of methamphetamine exposure are consistent among humans, fruit flies and other mammals.
Meanwhile, other studies have indicated that adding glucose to the diet of the fruit fly seemed to mitigate or somehow slow down some of the harsh consequences that result from chronic exposure to methamphetamine. The suggestion is that methamphetamine significantly compromises metabolism.
Also, it is often the case that humans who abuse methamphetamine are known to disproportionately consume sugar, particularly drinks high in sugar, which illustrates that methamphetamine exposure alters sugar metabolism as well.
Not withstanding all the research [previous and current] studies addressing methamphetamine exposure, none seems to clearly deduce how energy metabolism is impacted by methamphetamine.
Although, Pittendrigh and Walters of the University of Illinois have narrowed the possibilities down to two; methamphetamine either alters activity and feeding related behaviors or it alters protein function and/or alters how metabolic genes express themselves.
If you or anyone you know is suffering from methamphetamine addiction, please call us now. We can help.
Original article: news.illinois.edu
- Item Tag: crystal meth